本研究的另一位通讯作者Linghua Wang教授则指出，这些结果说明“对氧化磷酸化和谷氨酰胺代谢等癌症活跃代谢通路的探索，有望为套细胞淋巴瘤和其他淋巴瘤带来更好的临床预后。”

下一步，科学家们计划开展临床试验，评估IACS-010759治疗淋巴瘤的潜力。其中，他们也想纳入对伊布替尼产生耐药的患者组。如果试验取得成功，对于那些已经深陷绝望的患者而言，无疑将带来新的希望！

参考资料：

[1] Liang Zhang et al., (2019), Metabolic reprogramming toward oxidative phosphorylation identifies a therapeutic target for mantle cell lymphoma, Science Translational Medicine, DOI: 10.1126/scitranslmed.aau1167

[2] Study shows MD Anderson-developed drug effective in overcoming ibrutinib resistance in mantle cell lymphoma, Retrieved May 8, 2019, from https://www.mdanderson.org/newsroom/study-shows-md-anderson-developed-drug-effective-in-overcoming-ibrutinib-resistance-in-mantle-cell-lymphoma.h00-159303045.html